Los
Angeles County Department of Public Health Institutional
Review Board Policy (IRB) Regarding IRB Review of
Research and Related Activities Involving Human Subjects
The Dept. of Health and Human Services
regulations for the protection of human
subjects in research (45 CFR 46) include
five subparts. Subpart A, commonly
referred to as "the Common Rule",
provides a robust set of protections for
research subjects; subparts B, C, and D
provide additional protections for
certain populations in research; and
subpart E provides requirements for IRB
registration.
Please click the following link
HHS.gov to view the federal
regulations for the protection of human
subjects in research.
The Common Rule, subpart A, was revised
in 2018. In general, research initiated
before January 21, 2019, continues to
comply with the pre-2018 Common Rule
unless the institution chose to
transition it to the revised Common
Rule.
The Belmont Report identifies the basic
ethical principles that should underlie
the conduct of biomedical and behavioral
research involving human subjects, and
it forms the foundation for the federal
human subjects regulations known as the
"Common Rule" (45 CFR 46). The Belmont
Report was written by the National
Commission for the Protection of Human
Subjects of Biomedical and Behavioral
Research, and is a direct result of the
National Research Act of 1974.
Click
on the photo above to view a copy of the Belmont Report.
Click on the link below to view a
roster of the DPH IRB committee members.
IRB
committee roster