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Division of HIV and STD Programs
600 S. Commonwealth Ave., 10th Floor
Los Angeles, CA 90005
Phone:(213) 351-8000
Fax: (213) 738-0825
Office Hrs: 8 a.m.-5 p.m. M-F
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Post-Exposure Prophylaxis

Information for Providers

What is PEP?

  • Post-exposure prophylaxis (PEP) has been available for more than a decade.  PEP is an intervention to prevent HIV infection after a recent sexual or needlestick exposure.  PEP involves treatment with antiretroviral HIV drugs daily for 28 days. 

  • Studies suggest that PEP may be up to 80% effective in preventing an HIV seroconversion if the antiretroviral drugs are taken correctly with a high level of adherence.  For PEP to be effective, the prophylaxis must be started as soon as possible after the exposure, but no more than 72 hours. 

 What is a High-risk Sexual Exposure?

  • Sex with a known HIV-positive partner or a partner of unknown status and one of the following events:

    • Unprotected receptive anal sex or with a failed condom

    • Unprotected insertive anal sex or with a failed condom

    • Unprotected receptive vaginal intercourse or with a failed condom

    • Unprotected insertive vaginal intercourse or with a failed condom

Where can I Receive more Guidance on Services Related to PEP?

Where Can Patients be Referred for Treatment in LA County?

  • For more information call the LA County PEP warmline - (213) 351-7699

  • The Los Angeles Gay and Lesbian Center in Hollywood - (323) 860-5855 (Option 4)


Report an HIV or STD Case

Report and HIV or STD Case Here 

Need Assistance?

Have a Question about Services?

Call (800) 260-8787

Get Screened and Treated for HIV and STDs

Think You Were Exposed to HIV in the Last 72 Hours?


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