Post-exposure prophylaxis (PEP) has been
available for more than a decade. PEP is an
intervention to prevent HIV infection after a recent
sexual or needle stick exposure. PEP involves
treatment with antiretroviral HIV drugs daily for 28
Studies suggest that PEP may be up to 80%
effective in preventing an HIV seroconversion if the
antiretroviral drugs are taken correctly with a high
level of adherence. For PEP to be effective,
the prophylaxis must be started as soon as possible
after the exposure, but no more than 72 hours.
Pre-exposure prophylaxis (PrEP)
is a daily pill taken by
individuals, who are
are potentially exposed to
HIV. PrEP has been shown to
reduce the risk of HIV infection by up to 99% when
Is PrEP Affordable for my Patient?
PrEP is covered by health
insurance plans including Medi-Cal and Medicare.
If your patient is on either of these health
insurance plans, the prescription will not require
pre-authorization. The majority of private
health insurance plans include PrEP in their
formulary, although costs to the patient will vary
by plan and insurance provider.
assistance programs are available to patients on
private health insurance plans which can assist with
co-pay and deductibles.
Where can I Receive more Guidance on Services
Related to PrEP/PEP?
Clinicians seeking advice and consultation on PrEP
can call the hotline at 855 HIV PrEP (855-448-7737).
For more information on the services offered through
the PrEP-line, visit the national
Consultation Center website.
National Phone Consultation Center
warmline - (888)
448-4911 (9a.m. - 2 a.m. EST, 7 days a week)