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COVID-19 Vaccine

Healthcare Provider Information Hub

New and Noteworthy - COVID-19 Vaccination

Information about the COVID-19 vaccination program is changing frequently. Please check this site often and be sure to refresh your browser to view updates.

  • LAC DPH COVID-19 Update: COVID-19 Vaccine Additional Dose vs Booster and Vaccine Coadministration (9-10-21) This LAHAN explains the difference between the recommended additional doses for people who are moderately or severely immunocompromised and booster doses which are not yet authorized or recommended. In addition, influenza vaccination is currently recommended for all people 6 months or older with no contraindications and it can be administered COVID-19 vaccines. See LAHAN
  • CDC updated guidance: COVID-19 vaccination should not be delayed because of testing for TB infection. Testing for TB infection with one of the immune-based methods, either the tuberculin skin test (TST) or an interferon release assay (IGRA), can be done before, after, or during the same encounter as COVID-19 vaccination. (8-31-21) CDC Laboratory testing guidance.

Upcoming webinars and trainings

  • CDC Vaccine Training Modules (with CE) – new Janssen module. Modules include a general overview of immunization practices, and Janssen, Pfizer and Moderna vaccine storage, handling, preparation, administration, and documentation. Modules
  • COVID-19 Vaccine Training: What Every Clinician Needs to Know: NEJM Knowledge+ is launching this COVID-19 Vaccine Training, a free CME course that covers the fundamentals of the COVID-19 vaccines and the practicalities of how they are used. Available through June 30th, 2021. Learn more

Standing webinars

  • CDC COCA Webinars: Clinician Outreach and Communication Activity (COCA) Past COVID-19 topics include underlying medical conditions and severe COVID-19, vaccine safety and efficacy, and treating long COVID. Recorded webinars Subscribe.
  • CDC/IDSA COVID-19 Clinician Calls: July 17, July 31, August 14, and August 28 from 12-1pm PST. Past webinars include post-COVID conditions, variants, vaccination, and COVID-19 outcomes in at-risk groups. Recorded webinars Subscribe.

View recorded webinars

Becoming a COVID-19 Vaccination Provider

DPH greatly appreciates the partnership of health care providers and organizations to administer the COVID-19 vaccine to their patient population and their surrounding community members. If you are interested in becoming a vaccination provider, visit the Vaccination Partner Checklist to review all the requirements and additional information.

Detailed information regarding enrollment processes for joining the California COVID-19 Vaccination Program can be found at the CDPH EZIZ website at: https://eziz.org/covid/enrollment/.

Vaccination of adolescents

Information & Resources for Patients

DPH Resources (in English and Spanish)

  • Paratransit/transit services for people with disabilities webpage
  • Vaccine information for the public webpage: includes FAQs, vaccine and scams. Patients can also sign up to receive email newsletters with vaccine updates. Materials are available in multiple languages.
  • After you get a vaccine  webpage and handouts: includes information on side effects, V-safe and mental health resources.
  • When you are fully vaccinated webpages and handouts: explains what you can do after you are fully vaccinated, including when to wear a mask.
  • Vaccine records  webpage: includes information on how to get a copy of a vaccination record from CAIR, and digital vaccination records.
  • Promoting Vaccine Confidence checklist to help increase vaccine acceptance.

CDPH Resources

  • Vaccine Benefits and Risks Fact Sheets one page summaries of the FDA EUA fact sheets
  • Minor Consent for Pfizer vaccine guidance for providers and the public and template consent form

CDC Resources - Answering patients’ questions about COVID-19 vaccine:

FDA Resources

Recorded Webinars

  • CDC COCA Call: Influenza vaccination and coadministration with COVID-19 vaccines (9-9-21, 11am to 12pm PT) Presenters at this COCA Call will provide updates on the ACIP recommendations for 2021-2022 influenza vaccination and guidance for coadministration of these vaccines and COVID-19 vaccines. Free CME available. Presentation Slides
  • CDC COCA Call - Additional mRNA COVID-19 Vaccines for Moderately to Severely Immunocompromised People Tuesday, August 17, 11 a.m. to 12 p.m. PT. No registration required. Recording Slides
  • CDC/IDSA COVID-19 Clinician Call - Additional Vaccine Doses in the Immune-Compromised; the Latest on the Delta Variant, and Vaccination in Pregnant Women Saturday, Aug. 14, 12 p.m. PT. Recording Slides
  • CDC/IDSA COVID-19 Clinician Call: More on the Delta Variant, CDC Masking Recommendations and Updates from ACIP (recorded 7-31-21) This call included discussions of vaccine efficacy against variants of COVID-19 and of risk of transmission of the Delta variant. Watch the recording and download the PowerPoint.
  • Virtual ACIP Meeting CDC’s Advisory Committee on Immunization Practices met Thursday, July 22 from 9am to 2:30pm PT and focused on Guillain-Barré Syndrome (GBS) after vaccination with the Johnson & Johnson COVID-19 vaccine. Slides
  • IAS-USA Webinar COVID-19 Vaccines and the Viral Variants: New Aspects of Vaccine Research (CME available) This free webinar hosted by the International Antiviral Society-USA provided the latest data regarding COVID-19 vaccines, vaccine development process, and clinical trials, including the latest emerging issues and the likely next phases of the pandemic. Recorded webinar June 29 at 10 am PST. Recording
  • CDC/IDSA COVID-19 Clinician Call: Myocarditis after COVID-19 Vaccine; Plus Vaccine Q&A Recorded 6-26-21. This CDC/IDSA COVID-19 Clinician Call included case presentations and the latest data and discussions from the CDC Advisory Committee on Immunization Practices (ACIP) meeting on June 23-25. Recording Slides
  • Virtual ACIP Meeting  Items include: myocarditis after mRNA vaccines VaST assessment, mRNA vaccines in adolescents and young adults - benefit-risk discussion; overview of data to inform recommendations for additional doses of vaccines recorded 6-23-21 8am-1pm PT Agenda Meeting information Webcast Slides
  • Vaccines and Related Biological Products Advisory (VRPBAC) Committee Meeting Included CDC update on early safety data of Pfizer vaccination among adolescents and myocarditis and pericarditis following mRNA COVID-19 vaccination recorded 6-10-21 Briefing documents, slides, and recording
  • Becoming a COVID-19 Vaccinator - webinar for pediatricians from the American Academy of Pediatrics recorded 5-20-21. Webinar
  • CDC What Clinicians Need to Know About Pfizer-BioNTech COVID-19 Vaccination of Adolescents COCA Call. Recorded 5-14-21. Webinar
  • Providers of Pediatric Services: How to Enroll in the California COVID-19 Vaccination Program CDPH and CMA informational session on the enrollment process and requirements for providers of pediatric services that are interested in participating in the state's COVID-19 vaccination program. Recorded 5-11-21. Slides  Recording
  • COVID-19 in Pregnancy and Birth CMA webinar recorded on 5-11-21 View recording and download slides
  • Johnson and Johnson/Janssen COVID-19 Vaccine and Thrombosis with Thrombocytopenia Syndrome: Update for Clinicians. CDC COCA live webinar recorded on 4- 27-21Recording Slides
  • CDC/IDSA COVID-19 Clinician Call Multisystem Inflammatory Syndrome in Adults (MIS-A); Plus ACIP Meeting Update- Live webinar recorded 4-24-21 Recording, slides, and Q&A transcript
  • COVID-19 Clinician Call: The Johnson & Johnson Vaccine: Current Situation & Anticipated Next Steps 4-17-21 Recording  
  • CDC COCA webinar on cerebral venous sinus thrombosis (CVST) with thrombocytopenia associated J&J vaccine - including updated vaccine recommendations 4-15-21. Slides Recording
  • CDC/IDSA COVID-19 Clinician Call: COVID-19 in Pregnant Individuals; Plus Vaccine Q&A - Hosted in Partnership with ACOG. 4-10-21 Recording, slides, and Q&A transcript
View upcoming webinars

Contact us about Vaccines

Vaccine Administration Provider Line -Questions about vaccine distribution, storage and handling, and guidance on registering to receive the vaccine through the CDPH enrollment website.

Vaccine Clinical Provider Line –Clinical questions about COVID-19 vaccines including but not limited to contraindications, precautions, side effects, post vaccination assessment

  • Monday through Friday, 8:00am-5:00pm, call 213-240-7941. For time-sensitive questions after hours, call 213-974-1234 and ask for the on-call clinician

CDC/CISAvax (Clinical Immunization Safety Assessment Project) - Consults about COVID-19 vaccine safety. Healthcare providers can request a consultation from CISA COVIDvax for a complex COVID-19 vaccine safety question that is (1) about an individual patient residing in the United States or vaccine safety issue and (2) not readily addressed by CDC or Advisory Committee on Immunization Practices (ACIP) guidelines. CISA has vaccine safety subject matter experts in multiple specialties (e.g. ID, allergy/immunology, neurology, OB/GYN, pediatrics, geriatrics)

  • Contact CDC_INFO: 800-CDC-INFO (800-232-4636) or online
  • In case of an emergent clinical COVID-19 vaccine safety inquiry, healthcare providers can call the CDC Emergency Operations Center (EOC) Watch Desk at (770)-488-7100. The EOC Watch Desk will route emergency inquiries to the CISA COVIDvax on-call staff.

Medical professionals interested in supporting the COVID-19 response:

COVID-19 Vaccine Summary

Vaccine trial data, press releases, and information from the FDA are below:


  • Frenck et al. Safety, Immunogenicity, and Efficacy of Pfizer Vaccine in Adolescents. NEJM 2021; online publication May 27.
  • Walsh et al. Safety and immunogenicity of two RNA-Based COVID-19 vaccine candidates. NEJM 2020; online publication Oct 14.
  • Pfizer and BioNTech Conclude Phase 3 Study of COVID-19 Vaccine Candidate, Meeting All Primary Efficacy Endpoints Press Release 11-18-20
  • Phase 3 trial information 12-10-20 New England Journal of Medicine Safety and Efficacy of the BNT162b2 Covid-19 Vaccine  Editorial  Video summary
  • Pfizer vaccine: CDC webpage  FDA webpage (includes fact sheets for Healthcare Providers and  Recipients and Caregivers in 20 languages)
  • Pfizer vaccine efficacy at 6 months. Pfizer reported the vaccine to be highly effective against symptomatic cases up to 6 months after the second dose, and 100% effective in preventing COVID-19 cases in South Africa, where the B.1.351 lineage is prevalent. Press release 4-1-21
  • Pfizer vaccine efficacy in 12-15 year-olds The study demonstrated 100% efficacy in 12-15 year-olds. The company plans to submit an EUA application. 3-31-21 Press release
  • CDC recommends use of Pfizer COVID-19 vaccine in 12-15-yearolds(5-12-21) The CDC’s ACIP voted unanimously to recommend giving the Pfizer/BioNTech COVID-19 vaccine to children as young as 12 years of age. The CDC now recommends that this vaccine be used among this population, and providers may begin vaccinating them right away. See CDC Director Statement and ACIP Presentation Slides.


  • Moderna Announces TeenCOVE Study of its COVID-19 Vaccine in Adolescents Meets Primary Endpoint and Plans to Submit Data to Regulators in Early June Press Release 5-25-21
  • Jackson et al. An mRNA Vaccine against SARS-CoV-2-Preliminary report. NEJM 2020;20:1920-1931.
  • Moderna Announces Primary Efficacy Analysis in Phase 3 COVE Study for Its COVID-19 Vaccine Candidate Press Release 11-30-20
  • Moderna vaccine: CDC webpage  FDA webpage (includes fact sheets for Healthcare Providers and  Recipients and Caregivers in multiple languages)

Janssen (Johnson & Johnson)

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