County of Los Angeles
Department of Public Health
Acute Communicable Disease Control
313 N. Figueroa Street, #212
Los Angeles, CA 90012
Phone: (213) 240-7941
Fax: (213) 482-4856
Have questions about things like where to go for vaccinations or
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Acute Communicable Disease Control
(Back to Zika main page)
Zika Virus Testing Please
CDC released updated testing recommendations for Zika in
November 2019. Routine serological testing for Zika is
no longer recommended even for symptomatic persons. For
symptomatic pregnant women living in or with recent
travel to a Zika risk area with active dengue
transmission, nucleic acid testing for Zika and dengue
is recommended with IgM testing for dengue only. These
recommendations are due to the major decline of Zika
cases globally. Antibodies generated by a recent dengue
infection can cause Zika IgM to be falsely positive.
Testing guidelines may continue to be updated and can be
accessed on the CDC's Zika information for health care
providers webpage here.
Zika testing by PCR is available at
commercial laboratories and can be ordered using regular
clinical testing protocols. The
Los Angeles County
Public Health Laboratory (PHL) conducts confirmatory
Zika virus testing as needed.
TESTING AT THE LOS
ANGELES COUNTY PUBLIC HEALTH LABORATORIES (PHL)
PHL offers access to all recommended screening and confirmatory testing for Zika and related arboviral
infections. Some of this testing is sent to the
California State laboratory and/or CDC.
For specimen collection
consultation contact LAC
DPH Public Health
hours or holidays)
The Los Angeles County
Zika Virus Testing and Report Form must be completed for specimens to be
processed. Failure to complete required fields on the requisition forms will
result in specimen rejection or delayed testing. The form includes a two-page
reporting and test requisition form as well as the specimen requirements and
submission instructions found below. A separate test requisition form must be
submitted for each specimen type. The
Zika Virus Testing and Report Form available here.
Specimen Requirements for Zika Testing
Note: requested sample volumes are for adults.
* Specimens must be received within 24 hours of collection.
**Do not use glass vacutainer tube for blood collection. Do not use tubes that contain anti-coagulants.
***To optimize evaluation of possible Zika virus
infection on fetal tissues, please provide both formalin-fixed and unfixed tissues. If it is not possible to
provide both types of tissues, prioritize formalin-fixed
tissues. For additional information regarding collection
of fetal or infant tissues, please contact the Public
Health Laboratories for guidance.
Instructions for Test
Samples submitted with incomplete intake information,
incomplete patient history, incomplete or discrepant
patient sample identifiers and labeling information, or
incomplete test request forms will not be tested.
Provider may be required to complete additional forms for receiving results by fax if not currently a client of the
Los Angeles County PHL.
Convalescent serum or an additional serum sample may be requested depending on
Download and complete the required information for
Zika Virus Test Request Form. Separate testing forms (both pages 1 and 2) must accompany each specimen type.
The following information must be included on the form:
Facility/Submitter name, address, phone, and fax
Requesting provider name (Last, First) and contact information to enable
reporting of results
Patient name or unique patient identifier
Patient date of birth
Test(s) to be performed
Date and time of specimen collection
If the patient or provider are unable to obtain phlebotomy services,
contact the Los Angeles Acute Communicable Disease Control Program (ACDC) for assistance, approval, and referral to a Los Angeles County Public Health Clinic.
Specimens must be labeled with the following information:
Patient name (Last, First)
Date of Birth
Collection Date and Collection Time
Specimen Processing and Packaging
Proper storage and transport conditions preserve analyte integrity within the sample. Leaking specimens will also be rejected:
Clinics able to process specimens may centrifuge blood and transfer serum to a separate, sterile,
Public Health has made reasonable efforts to provide accurate translation. However, no computerized translation is perfect and is not intended to replace traditional translation methods. If questions arise concerning the accuracy of the information, please refer to the English edition of the website, which is the official version.