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Acute Communicable Disease Control

    

Acute Communicable Disease Control


Contact Information
County of Los Angeles
Department of Public Health
Acute Communicable Disease Control
313 N. Figueroa Street, Room 212
Los Angeles, CA 90012
Phone: (213) 240-7941
Fax: (213) 482-4856
E-Mail:acdc2@ph.lacounty.gov
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Acute Communicable Disease Control
Escherichia coli O157:H7

Escherichia coli O157:H7, a Gram-negative bacillus, is a specific serotype of the shiga toxin producing class of
E. coli
(STEC) and the most common such serotype in the US. Incubation period is 2-8 days. Shiga toxins cause
abdominal cramps and watery diarrhea, often developing into bloody diarrhea; fever is uncommon. Likely modes of transmission include foodborne (e.g., undercooked ground beef, fresh produce, unpasteurized juice, raw milk) and person-to-person (e.g., day-care settings). There also have been outbreaks associated with exposure to animals
and their environments and recreational water exposure. All E.coli O157:H7 isolates are confirmed by the Los
Angeles County Public Health Laboratory.

Hemolytic uremic syndrome (HUS) is a clinical diagnosis and may or may not be associated with E. coli O157:H7. Children younger than 5 years of age are at highest risk for hemolytic uremic syndrome (HUS), a clinical complication consisting of hemolytic anemia, thrombocytopenia, and kidney failure. Adults may acquire thrombotic thrombocytopenic purpura (TTP) after STEC infection.

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