LACDPH is aligned with the California Department of Public Health immunization recommendations which are informed by the American Academy of Pediatrics (AAP). The AAP develops childhood vaccine recommendations based on extensive research and evidence and strongly recommends on-time routine immunization of all children and adolescents according to the recommended schedule.

Click here for the California Department of Public Health 2025 recommended vaccines for infants and children from birth through 6 years.

• Respiratory Syncytial Virus (RSV) immunization – Infants under 8 months old who are born during or entering their first RSV season (October through March) should receive one dose of nirsevimab or clesrovimab to protect against RSV, pneumonia and bronchiolitis in young infants if their birth parent was not vaccinated during pregnancy. Infants and children 8 to 19-months-old who are at high risk for RSV and entering their second RSV season should also receive one dose of nirsevimab.
• Hepatitis B vaccine – 3-4 dose series with the first dose given at birth, is recommended to protect against Hepatitis B.  This virus can cause long term liver damage in children and as adults.
• Rotavirus (RV) vaccine – 2 or 3 dose series is recommended to protect against rotavirus, which causes severe diarrhea, fever, vomiting and dehydration.
• DTaP (Diphtheria, tetanus, and pertussis [whooping cough]) vaccines – A 5-dose series is recommended, beginning at 2 months, to protect against diphtheria, tetanus and pertussis (whooping cough), which are especially dangerous for infants.
• Haemophilus influenzae type b (Hib) vaccine – 3-4 dose series beginning at 2 months of age, provides protection against this bacterial infection which can result in brain infection (meningitis), lung infection (pneumonia) and bloodstream infection (sepsis).
• Pneumococcal conjugate vaccine - 4 dose series beginning at age 2 months is recommended to provide protection against this bacterium that can cause ear infections, lung infection (pneumonia), bloodstream infection (sepsis) and brain infection (meningitis).
• Inactivated poliovirus vaccine (IPV) – 4 doses are recommended starting at 2 months of age can prevent polio, a disease resulting damage of nerves, causing long term damage and inability to move parts of one’s body (paralysis).
• COVID-19 Vaccine - Vaccine is recommended for all children aged 6 months and older whose parent or guardian desire protection. In addition, all young children aged 6 – 23 months, children aged 2-18 years with underlying medical conditions or have never been vaccinated against COVID-19, and children who are in close contact with other with risk factors are recommended to complete their primary series.
• Influenza (Flu) vaccine – 1-2 dose series is recommended for infants 6 months of age and older depending on the number of doses received in previous years.
• Measles, Mumps, Rubella (MMR) vaccine – 2 dose series beginning with the first at 12 – 15 months and a 2^nd dose at 4 – 6 years-old is recommended to provide protection against measles, mumps and rubella (German measles).
• Varicella vaccine - 2 dose series beginning at 12 months of age is recommended to prevent chickenpox which can cause rash, fever, infected blisters, brain swelling and/or pneumonia. A 2^nd dose is recommended at 4-6 years of age.
• Hepatitis A vaccine – 2 dose series beginning at age 12 months. A 2^nd dose is recommended 6 months later can protect against hepatitis A virus, which can cause fever, loss of appetite, jaundice and long-term liver, kidney, or blood disorders.

Children living with chronic diseases such as diabetes or asthma, and those who are immunocompromised, may have more difficulty protecting themselves again certain diseases, making vaccinations extremely important.

• COVID-19 Vaccine - Additional doses may be indicated for moderately to severely immunocompromised populations.
• Respiratory Syncytial Virus (RSV) immunization  – 1 dose is recommended for infants and toddlers at ages 8-19 months entering their  2^nd RSV season (October through March) at risk for severe disease.
• Pneumococcal conjugate vaccine – additional doses may be indicated for your child if they have a chronic disease affecting their heart, lungs, or kidneys.
• Hepatitis B vaccine – additional doses may be indicated in certain populations.
• Haemophilus influenzae type b (Hib) vaccine – additional doses may be indicated for children with certain conditions, such as asplenia (no spleen), sickle cell, HIV, or undergoing chemotherapy treatment.
• Meningococcal vaccine – this vaccine is recommended for children with certain immunocompromising conditions, such as asplenia (no spleen) sickle cell, or HIV.

*One Hib dose must be given on or after the 1st birthday regardless of previous doses. Required only for children younger than 5 years old.

• DTaP=diphtheria toxoid, tetanus toxoid, and acellular pertussis vaccine
• Hib=Haemophilus influenzae, type B vaccine
• Hep B=hepatitis B vaccine
• MMR=measles, mumps, and rubella vaccine
• Varicella=chickenpox vaccine