Primary Aims Aerobic Exercise to Improve Outcomes of Treatment for Methamphetamine Dependence

Characterize effects of an aerobic and resistance exercise intervention (“Exercise”) compared to health education (“Education”) in terms of drug use after discharge from residential drug treatment in a population of MA-dependent individuals.
Characterize effects of Exercise on MA craving and negative affective states, including anxiety, depression, and anhedonia, among participants in residential treatment for MA dependence.
Characterize effects of Exercise on neurocognitive functioning.
Characterize variations in health-related outcomes among participants in the Exercise condition compared with those in the Education condition.
Examine changes in dopamine D2/D3 receptor availability in abstinent MA-dependent participants assigned to the Exercise group compared to a subsample of participants in the Education (control) group (n = 15 per group).
Examine differences in addiction-relevant behaviors (per ASI-type measures) according to intervention condition.

Characterize effects of an aerobic and resistance exercise intervention (“Exercise”) compared to health education (“Education”) in terms of drug use after discharge from residential drug treatment in a population of MA-dependent individuals.