Pre-Exposure Prophylaxis
Physicians CME Certificate

View the Rx for Prevention Article

This enduring material has been approved for [ 1 ] AMA PRA Category 1 Credit™.

Original release date: May 9, 2017.  Review date: April 24, 2018.  Termination date: May 9, 2020.

Continuing Medical Education Credit(s)

Physicians – to obtain a CME Certificate, read the article, including the toolkit, and click here.

Other Health Care Providers – to obtain a Certificate of Attendance, read the article, including the toolkit, and click here.

Article Summary

Improvements in laboratory diagnostics and treatment regimens for TB infection, along with the recent recommendation by the US Preventive Services Task Force (USPSTF) for screening asymptomatic adults at risk for TB infection, enable primary care providers to take on a larger role in the fight against TB. This article will summarize the key steps for recognition and treatment of TB disease and TB infection and showcase new tools from the LA County TB Control Program (TBCP) designed to help primary care providers detect and treat TB infection.

Target Audience

The target audience is all primary care health care providers in Los Angeles County.  

Learning Objectives

At the conclusion of the article, participants will be able to:

  1. Discuss what percent of TB infection progresses to active TB.
  2. List the populations in Los Angeles County at highest risk for TB infection.
  3. Explain when testing with interferon gamma release assay (IGRA) is preferred over tuberculin skin testing (TST).
  4. Discuss newer rifamycin based short course options for TB infection treatment, including selection criteria, dosing, and duration of therapy.


Julie Higashi, MD, PhD is the Director of the Tuberculosis Control Program, Los Angeles County Department of Public Health.

Accreditation Statement

The Los Angeles County Department of Public Health is accredited by the Institute for Medical Quality/California Medical Association (IMQ/CMA) to provide continuing medical education for physicians.

The Los Angeles County Department of Public Health designates this enduring activity for a maximum of [ 1 ] AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses receive a Certificate of attendance. This activity is designated for [ 1 ] AMA PRA Category 1 Credit(s)™. According to the California Board of Registered Nursing, the Continuing Medical Education is acceptable for meeting RN continuing education requirements, as long as the course is Category 1, and has been taken within the appropriate time frames.


No relevant financial relationships were disclosed by the author or the planners.

This activity is offered by an accredited CMA-CME provider and is not commercially supported.

Contact Information

For questions or further information about this article, please contact: The Los Angeles County TB Control Program  (213) 351-8003 or visit

For further information about DPH CME please email: