Acute Communicable
Disease Control

Contact Information
County of Los Angeles
Department of Public Health
Acute Communicable Disease Control
313 N. Figueroa Street, #212
Los Angeles, CA 90012
Phone: (213) 240-7941
Fax: (213) 482-4856

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Acute Communicable Disease Control
Novel Multi-Drug Resistant Organisms

Local and national surveillance has identified novel forms of multi-drug resistant organisms (MDROs) that need to be detected and contained before they spread. Many of these organisms are difficult to treat, have been associated with international travel, and have the potential to spread rapidly.

Healthcare facilities and laboratories should report any of the following organisms are detected the Acute Communicable Disease Control Program within 1 working day:
  • Atypical Candida auris (such as echinocandin-or pan-resistant cases)
  • Non-KPC-carbapenemase-producing Enterobacterales
  • Carbapenemase-producing Acinetobacter baumanii
  • Carbapenemase-producing Pseudomonas aeruginosa
  • Pan-resistant organisms

LACDPH used CDC guidance to are further categorize these into four tiers based on their local epidemiology and clinical significance, which can be reviewed in our LACDPH MDRO Containment Tiers. Tier 1 and Tier 2 organisms warrant additional investigation from LACDPH staff to prevent the spread of these concerning organisms as much as possible. For example, when a Tier 2 organism is identified, screening should be performed to detect and contain any other cases. Additional guidance is coming soon!

Reporting Instructions


Monthly MDRO Lab Newsletter


Los Angeles County 2022 Multi-Drug Resistant Organism (MDRO) Report
LAC DPH Transferring Guidance for MDROs - This document provides some guidance on how discharging and receiving facilities can ensure that each patient's MDRO status is clearly communicated during the transfer process.
NDM-CRAB Transfer Recommendations and FAQs for Healthcare Facilities
NDM-CRE Transfer Recommendations and FAQs
N-MDRO Newsletter
Spotlight on Candida auris
N-MDRO Newsletter
Issue I (January 2019) - Describes findings from our N-MDRO surveillance to date along with recommendations
CPO Wallet Card: Healthcare facilities can provide this to patients/residents that are infected/colonized with a carbapenemase-producing organism (CPO) to remind them that they made need special precautions when receiving health care at a facility or at home.
CDPH Enhanced Standard Precautions for Skilled Nursing Facilities (SNF), 2019: This updates guidance on safely caring for skilled-nursing facility residents suspected or known to be positive for multidrug-resistant organisms (MDRO).

Useful Links:
CDC Containment Strategy Responding to Emerging AR Threats

See Also
Antibiotic Resistance


Healthcare Outreach
Public Health has made reasonable efforts to provide accurate translation. However, no computerized translation is perfect and is not intended to replace traditional translation methods. If questions arise concerning the accuracy of the information, please refer to the English edition of the website, which is the official version.
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